Lyapunov exponent(LE) is an important indicator to describe the nature of chaotic dynamical systems. It’s difficult to calculate LE accurately and fast with small sample size. In this paper, an algorithm for computing LE based on support vector regression(SVR) is proposed, the parameters of support vector machine(SVM) model are optimized by using quantum genetic algorithm(QGA), and the formula of the LE based on SVR is derived. Simulation results show that the proposed algorithm is feasible and effective with much less samples.