According to the near space vehicle with disturbances, whose wing sweep angle is variable, the problem of designing a fuzzy adaptive controller is considered for multi-input and multi-output nonlinear systems based on multiple models switching. The common Lyapunov function and the controller are simultaneously designed. The dynamic surface control approach is used to avoid the problem of the explosion of calculation. The adaptive fuzzy systems and the robust controllers are adopted to eliminate the influence of the unknown disturbances on line. Simulation results show the effectiveness of the proposed method.