Wireless sensor networks are more widely used in indoor environments. However, the study of wireless channel fading model is not yet mature. Therefore, for the typical office and residential environments, the fading characteristics of channel transmission for wireless sensor nodes are tested, the testing data are fitted, and the corresponding model is presented. The fitting results show that, in the case of large-scale fading, the proposed three-order polynomial logarithmic distance path loss model can better characterize the channel fading in the indoor environment. The proposed model and analytical results have important significance for the key technology of indoor wireless sensor networks.