For perishable products, when a supplier is in the buyer's market of a supply chain node, it usually requires retailers to pay a certain proportion of purchase cost in advance as a deposit. The pricing and inventory lot-size policies for non- instantaneous deteriorating items with stochastic demand and promotional efforts are studied. The payment policy and shortage are considered. Under certain conditions, retailers get the optimal replenishment cycle and local optimal pricing strategy, and the corresponding solving algorithm is proposed. Numerical results show that, with the increase of the interest rate and proportion of advanced purchase cost payments, retailers' profits will be reduced, the prepayment period and prepayments number both have negative influence on the optimal profit, actively promote sales strategies can effectively enhance retailers' profits.