The combination prediction of ship rolling motion is proposed based on single model screening. Single model is selected by using co-integration theory and redundant method based on non-negative constraints, and the combination model is established by using the screened single models. The combination model is used to predict the situation of one certain type of ship sailing in the beam sea condition. Simulation results show that the model used in contrast to single model and combination model of single model non-screening can quickly and accurately predict the time series of ship rolling, and also show the feasibility and effectiveness of the proposed.