To achieve the cooperative attack against a same target for multi-missiles, an approach to design the time-cooperative distributed guidance law is proposed, which is applicable to the situation with or without angular constraint. With each missile subsystem as a homogeneous network node, the time-cooperative guidance model for multi-missiles is built, which takes each missile’s time-to-go plus designated bias as the outputs. The distributed control scheme of the system is designed to reduce the difference among the outputs of subsystems. The communication topology condition to guarantee the time-cooperativeness of multi-missiles is given by analyzing the features of the homing guidance of missile with consideration of the convergence condition of the general cooperative control system. Finally, simulation results show the effectiveness of the proposed approach.