：To restore the topology failure of mobile underwater wireless sensor networks(MUWSNs) brought by dynamic evolution features, a mobility model used to simulate the motion of underwater entities is constructed with considering the influence of water flow to MUWSNs network topology. For restoring topology failure of MUWSNs caused by mobility of underwater entities, a topology healing algorithm is proposed. The fish-swarm algorithm is used to deploy AUVs nodes, thus the system failure perception mechanism, messaging mechanism, and mobile healing scheme are constructed. On the basis of the healing algorithm, the fish inspired MUWSNs topology optimization scheme is designed. The two groups experimental results show the feasibility of this model and the effectiveness of the proposed algorithm. It is found in simulations that the algorithm can ensure network coverage maintained at about 90%, and topology optimization scheme can improve the network coverage.