The longitude integrated guidance and control design approach of the hypersonic vehicle is studied. The longitude design model for designing the integrated guidance and control law is built, and by combining nonlinear disturbance observer and adding a power integrator technique, a new integrated guidance and control law is proposed. Based on the relevant foundation theory, the cascaded system is demonstrated to be finite-time stabilized. The proposed approach can make the guidance and control systems coordinate well, and make full use of the control capability of vehicle. Compared to the back-stepping based sliding-mode integrated guidance and control approach according to the nominal simulation, the adding a power integrator based approach is effective and much better. The simulations with different maneuvering target and parameter deviation verif the strong robustness of the proposed method.