The paper studies a graphic evaluation and review techuique(GERT) network optimization problem with uncertain project activity time and resources invested in the collaborative development process of airliners. Firstly, the development process of the complex product is characterized by a GERT network which is considered as a basis of calculating the project completion cost, then a form denoting the completion probability is proposed considering the influence of project duration and resources involved in the project. Then, to adjust and optimize the time-cost-resources involved in the project when each activity time and the total project completion time are uncertain, a time planning and resource scheduling optimization model is proposed under the limitation of the total completion time, resources and implementation probability, and a difference evolutionary heuristic algorithm is developed to solve the model. Finally, as the comprehensive trial-manufacture process of airliners is the key to measure whether the project is completed on schedule, this paper considers it as the background of the case study to verify the feasibility and effectiveness of the proposed method.