It is an unavoidable trend that internet will develop into internet of things, and the technique of internet of things will surely be applied into the intelligent management of research infrastructure. Based on internet of things, the various parameters of research equipments can be extracted by sensors, which then send the information into cloud server or other types of data management center for processing. As wireless transmission is needed, there is always a problem of reliability for data transmission. If the signal of the equipement cannot be transmitted to the shared data centre, it may influence the the intelligent management of the equipments. In this paper, the system for research infrastructure is simplized to a non-linear multi-state system, and an initial model is constructed to model the reliability of intelligent management of research infrastructure based on internet of things. The technological process and the computational complexity for maximum number of nodes and paths are shown in details. Finally, the procedures are illustrated with an illustrative example to verify the given technological process.